fsaHSA & FSA accepted; best-value for top quality care
fsaSame-day mental health, weight loss, and primary care appointments available
Excellent
unstarunstarunstarunstarunstar
staredstaredstaredstaredstared
based on 0 reviews
fsaAccept major insurances and cash-pay
fsaHSA & FSA accepted; best-value for top quality care
fsaSame-day mental health, weight loss, and primary care appointments available
Excellent
unstarunstarunstarunstarunstar
staredstaredstaredstaredstared
based on 0 reviews
fsaAccept major insurances and cash-pay

Sodium oxybate (Xyrem) online prescription

Sodium oxybate, marketed under the brand name Xyrem, is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of cataplexy and excessive daytime sleepiness in individuals aged 7 years and older with narcolepsy.

Interested in getting evaluated for a sodium oxybate prescription online? Connect with a licensed provider through Klarity Health and receive care in as little as 24 hours.* Providers will assess your symptoms and determine if sodium oxybate or another treatment is appropriate.

Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.

a picture of a provider who can offer Sodium oxybate (Xyrem) prescription online if medically appropriate

Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.

Online narcolepsy treatment for you and about you

You’re unique. And your needs are too. You deserve narcolepsy treatment from a provider committed to you. That’s why you can find a narcolepsy specialist on Klarity Health and access:

Narcolepsy assessment and treatment online in 24 hours*

Narcolepsy assessment and treatment online in 24 hours*

From an experienced, board-certified healthcare professional.

Narcolepsy medication prescribed online

Narcolepsy medication prescribed online

or in-person through treatment tailored to you**

Confidential, personalized care

Confidential, personalized care

Your information is private, secure, and 100% HIPAA compliant.

*Your provider will discuss treatment options with you, which may or may not include medication.

Book an appointment with experts for the treatment of narcolepsy

Klarity Health connects you with experienced, licensed providers who specialize in the treatment of narcolepsy. Select your state to see available providers.

Top-rated providers available for you

Amethyst Maxey, FNP-CAPRN
4.98
Amethyst Maxey, FNP-CAPRN
Specializes in Psychiatry, Mental Health
Sawyer Flandreau, FNP-BC
5.0
Sawyer Flandreau, FNP-BC
Specializes in Family Medicine, Mental Health
Melissa Tam, FNP-BC
5.0
Melissa Tam, FNP-BC
Specializes in Internal Medicine, Family Medicine
Derek Timbs, FNP-BC
4.96
Derek Timbs, FNP-BC
Specializes in Weight Loss, Preventive Medicine
Margaret Gallagher, PhD, FNP-BC
5.0
Margaret Gallagher, PhD, FNP-BC
Specializes in Weight Loss, Mental Health
Laurie Jean Foley, PMHNP-BC
5.0
Laurie Jean Foley, PMHNP-BC
Specializes in Weight Loss, Mental Health
Kate Graen, PA-C
4.96
Kate Graen, PA-C
Specializes in Psychiatry, Mental Health
Ernest Emery, AGACNP-BC
5.0
Ernest Emery, AGACNP-BC
Specializes in Psychiatry, Internal Medicine
Noussaiba Ayour, PA
5.0
Noussaiba Ayour, PA
Specializes in Urgent Care, Behavioral Medicine
Amethyst Maxey, FNP-CAPRN
4.98
Amethyst Maxey, FNP-CAPRN
Specializes in Psychiatry, Mental Health
Sawyer Flandreau, FNP-BC
5.0
Sawyer Flandreau, FNP-BC
Specializes in Family Medicine, Mental Health
Melissa Tam, FNP-BC
5.0
Melissa Tam, FNP-BC
Specializes in Internal Medicine, Family Medicine
leftArrow
rightArrow
Derek Timbs, FNP-BC
4.96
Derek Timbs, FNP-BC
Specializes in Weight Loss, Preventive Medicine
Margaret Gallagher, PhD, FNP-BC
5.0
Margaret Gallagher, PhD, FNP-BC
Specializes in Weight Loss, Mental Health
Laurie Jean Foley, PMHNP-BC
5.0
Laurie Jean Foley, PMHNP-BC
Specializes in Weight Loss, Mental Health
leftArrow
rightArrow
Kate Graen, PA-C
4.96
Kate Graen, PA-C
Specializes in Psychiatry, Mental Health
Ernest Emery, AGACNP-BC
5.0
Ernest Emery, AGACNP-BC
Specializes in Psychiatry, Internal Medicine
Noussaiba Ayour, PA
5.0
Noussaiba Ayour, PA
Specializes in Urgent Care, Behavioral Medicine
leftArrow
rightArrow
Medically reviewed by Itunu

About sodium oxybate

a picture of sodium oxybate

About sodium oxybate

What is sodium oxybate?
Sodium oxybate is a central nervous system depressant prescribed to treat cataplexy and excessive daytime sleepiness in narcolepsy. It is available in two formulations: an oral solution marketed as Xyrem and an extended-release oral granule suspension formulation called Lumryz. Both contain sodium oxybate as the active ingredient. Sodium oxybate is the sodium salt of gamma-hydroxybutyrate (GHB). 

Due to its potential for misuse, sodium oxybate is classified as a Schedule III controlled substance under the Controlled Substances Act. To manage risks, both Xyrem and Lumryz are only available through restricted distribution programs, known as the Xyrem and Xywav REMS, and Lumryz REMS, respectively.

How to get a sodium oxybate prescription online?

Obtaining a sodium oxybate prescription online involves a few steps:

  • Booking a virtual visit: Use a telehealth platform like Klarity Health to schedule an appointment with a licensed medical provider.
  • Medical review: During the visit, the provider will assess your symptoms, review your health history, and determine if sodium oxybate is appropriate for you.
  • Prescription fulfillment: If prescribed, your sodium oxybate prescription will be sent to your preferred pharmacy for pickup or home delivery.

How does sodium oxybate compare to other medications?

When considering treatment options for narcolepsy, it’s important to compare the efficacy, side effect profiles, and administration routes of available medications. Below is a comparison of sodium oxybate with other commonly used treatments:

MedicationUse CaseSide EffectAdministration
Sodium Oxybate
(Schedule III)
Narcolepsy (cataplexy, daytime sleepiness)CNS depression, abuse potentialOral solution, oral suspension (once in two divided doses)
Modafinil
(Schedule IV)
Narcolepsy, shift work sleep disorder, sleep apneaHeadache, lower risk of abuse and misuse)Oral tablet (once daily)
Armodafinil
(Schedule IV)
Narcolepsy, shift work sleep disorder, sleep apneaHeadache, lower risk of abuse and misuseOral tablet (once daily)

Sodium oxybate is  used for treating both cataplexy and excessive daytime sleepiness in narcolepsy. Modafinil and armodafinil are alternatives that primarily address daytime sleepiness and  it has a lower risk of abuse and misuse compared to Sodium Oxybate. The choice of medication should be based on individual patient needs and under the guidance of a healthcare provider.

How Klarity Health works

  1. Find a provider and book an appointment in minutes

    1. Meet your provider online for care and a prescription if needed

      1. Pick up your medication at a pharmacy if prescribed

        1. Get 24×7 ongoing support. Book a follow-up anytime

          With Klarity Health, you’re in good company

          Read through stories from real patients who received treatment from healthcare providers on Klarity.

          FAQs about getting sodium oxybate prescription online

          *Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.


          The information provided in this article is for educational purposes only and should not be construed as medical advice. Controlled substances may not be appropriate for all patients and any mention of these medications is for educational purposes only, not for marketing or encouraging self-diagnosis. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.

          logo
          All professional services are provided by independent private practices via the Klarity technology platform. Klarity Health, Inc. does not provide medical services.

          PO Box 5098 Redwood City, CA 94063

          100 Broadway Street, Redwood City CA, 94063

          Join our mailing list for exclusive healthcare updates and tips.

          Stay connected to receive the latest about special offers and health tips. By subscribing, you agree to our Terms & Conditions and Privacy Policy.
          logo
          All professional services are provided by independent private practices via the Klarity technology platform. Klarity Health, Inc. does not provide medical services.

          PO Box 5098 Redwood City, CA 94063

          100 Broadway Street, Redwood City CA, 94063

          If you’re having an emergency or in emotional distress, here are some resources for immediate help: Emergency: Call 911. National Suicide Prevention Lifeline: call or text 988. Crisis Text Line: Text HOME to 741741.
          Hipaa
          © 2025 Klarity Health, Inc. All rights reserved.