Adderall XR vs Adderall: which one should you take for ADHD?
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Written by Klarity Editorial Team
Medically Reviewed by Dr. Zoe Russell
Published: May 16, 2024
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Navigating the variety of medications for attention deficit hyperactivity disorder (ADHD) can be frustrating and confusing, especially when the medications are similar. But Adderall XR vs Adderall is one of the easier comparisons to make.
Adderall (amphetamine/dextroamphetamine) or Adderall IR, the standard formula, is one of the most commonly prescribed ADHD medications for reducing symptoms and regulating brain function. Adderall XR (amphetamine/dextroamphetamine) is the same medication in extended-release form.
In this article, we compare the 2 forms of Adderall so that you can have an informed discussion with your healthcare provider about which is the best choice for your ADHD symptoms.
If you suspect you have ADHD, Adderall and Adderall XR could help relieve your ADHD symptoms. Klarity Health matches patients with experienced healthcare providers for personalized ADHD treatment, including prescription medication.
Adderall XR vs Adderall, what’s the difference?
Adderall XR and Adderall are the same medication in different formulations. Adderall XR is an extended-release form that lasts for up to 12 hours. It’s taken just once a day. Adderall (Adderall IR for instant release) works immediately and lasts 4 to 6 hours. You may take it twice a day.
Both are central nervous system (CNS) stimulants that help people with ADHD symptoms pay attention, control behavioral issues, organize tasks, and listen. They regulate the effects of neurotransmitters in the brain — specifically dopamine and norepinephrine.
Whether Adderall XR vs Adderall is better for you depends on your needs and lifestyle. Speak with an ADHD healthcare provider about which ADHD medication might best fit your daily needs.
Adderall XR is a stimulant medication delivered in a time-released formula that remains in the system longer than standard Adderall. Brand-name Adderall XR comes in 5, 10, 15, 20, 25, and 30 milligram oral capsules. The slow-dissolving capsules release a steady dose of the active ingredients into the bloodstream. Adderall XR can be taken with or without food and should only be taken once a day as it lasts in your system for at least 12 hours.
Side effects of Adderall XR
Common side effects for adults taking Adderall XR include: dry mouth, loss of appetite, trouble sleeping, headache, weight loss, nausea, anxiety, agitation, dizziness, fast heartbeat, diarrhea, and weakness.
More severe, but less common side effects of Adderall XR include: slowing of growth in children, seizures, circulation problems in fingers and toes, serotonin syndrome, and new or worsening tics.
Warnings for taking Adderall XR
Adderall XR is a Schedule II controlled substance with a high potential for misuse, abuse, and addiction. It has a boxed warning for abuse, misuse, and addiction. If you have a known structural heart abnormality, cardiomyopathy, serious cardiac arrhythmia, or other serious heart problems, avoid Adderall.
What is Adderall?
Adderall (amphetamine/dextroamphetamine), like Adderall XR, is a combination of amphetamine and dextroamphetamine, 2 CNS stimulants. The standard form of Adderall is quick-acting, as opposed to the long-lasting formulation in Adderall XR. Adderall comes in tablet form in 5, 7.5, 10, 12.5, 15, 20, and 30 milligram dosages and is taken no more than twice a day.
Find a provider and get the best ADHD medication for you on Klarity Health
Klarity Health is an online platform where you can find a licensed ADHD medical professional who can identify the right medication for you. At Klarity Health, you can easily book an appointment within as little as 24 hours and get treatment without leaving home.*
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Controlled substances may not be appropriate for all patients and any mention of these medications is for educational purposes only, not for marketing or encouraging self-diagnosis. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
If you’re having a mental health crisis or experiencing a psychiatric emergency, it’s crucial to seek immediate help from a mental healthcare professional, such as a psychiatrist, psychologist, or therapist. You can also call your local emergency services, visit your nearest emergency room, or contact a crisis hotline, such as the National Suicide Prevention Lifeline, by calling or texting 988 or dialing the Lifeline’s previous phone number, 1-800-273-TALK (1-800-273-8255) in the U.S.
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