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12 min read

Gabapentin for anxiety: Is Gabapentin the right choice for you?

Written by Klarity Editorial Team

Published: Jan 19, 2024

Medically Reviewed by Dr. Zoe Russell

Table of contents

Living with anxiety can feel like a relentless battle, and finding the right anxiety treatment often seems just as challenging as the mental health condition itself. 

Gabapentin, a prescription medication originally used for neurological disorders, has become beneficial for many grappling with anxiety symptoms. Understanding Gabapentin’s role and effectiveness in treating anxiety is crucial for those considering it as a treatment option. 

This article covers the science behind Gabapentin, its specific uses for various anxiety-related conditions, and its overall efficacy. We also discuss the practical aspects of using Gabapentin to treat anxiety disorders, including dosage guidelines, expected timelines for seeing results, and potential side effects. 

Whether you’re considering getting prescribed Gabapentin for anxiety, looking into another medication, or exploring other types of treatment like therapy to help with anxiety, the providers on Klarity will offer you support for your mental health needs.

Find a provider on Klarity today to see if Gabapentin for anxiety is the right choice for you.

What is Gabapentin? 

Gabapentin is a medication originally developed for treating epilepsy, but it has found a significant role in managing various neurological conditions. Its effectiveness stems from its ability to influence neurotransmitters in the brain, offering relief from symptoms of nerve pain and seizures. 

Beyond its primary use, Gabapentin has gained attention for its off-label application in treating anxiety disorders. What sets Gabapentin apart compared to other anxiety medications is its unique action on the nervous system. This distinct mechanism of action provides an alternative treatment route for those who may not respond well to conventional anxiety medications.

How does Gabapentin work?

Gabapentin’s mechanism of action in treating anxiety is centered around its effect on the brain’s neurotransmitters. It is structurally similar to GABA, a neurotransmitter that naturally reduces the brain’s excitability. By mimicking GABA, Gabapentin helps in relaxing neural activity, which is often heightened in anxiety disorders, leading to calm down anxiety symptoms.

This medication also influences the way nerve signals are transmitted in the brain, further contributing to its anti-anxiety effects. Unlike many traditional anxiety medications that focus on serotonin or dopamine pathways, Gabapentin’s unique action on GABA pathways provides a different approach.

What conditions does Gabapentin treat?

Gabapentin’s versatility extends beyond its primary use in neuropathic pain and epilepsy to a variety of off-label applications, notably in mental health care. It’s particularly effective in treating several forms of anxiety, such as generalized anxiety disorder (GAD), severe anxiety, social anxiety, and panic disorder. 

Gabapentin is also explored as a potential treatment for other conditions, like restless leg syndrome and hot flashes, showcasing its multifaceted therapeutic capabilities. Its utility in treating a variety of symptoms, from physical pain to psychological distress, underlines its role as a versatile and important medication in modern healthcare.

How effective is Gabapentin as an anxiety treatment?

The efficacy of Gabapentin in treating anxiety disorders is attributed to its unique ability to modulate the nervous system, providing a sense of calm and relief from anxiety symptoms. Clinical studies have shown promising results, with many patients experiencing a significant reduction in anxiety symptoms, particularly in cases where traditional treatments have fallen short or caused adverse effects.

Gabapentin’s effectiveness as an anxiety treatment is further supported by anecdotal evidence from patients who have found relief after struggling with other treatments. This growing body of evidence suggests Gabapentin’s potential as a viable and effective alternative for managing anxiety, providing new avenues for treatment and hope for those affected by anxiety disorders.

How to take Gabapentin

Taking Gabapentin for anxiety involves a specific regimen that must be closely followed for safety and efficacy. It’s usually started at a low dose and gradually increases to an effective level to minimize side effects. 

The key to effective treatment lies in maintaining a consistent routine, taking Gabapentin at the same time each day, and ensuring steady prescription drug levels in the bloodstream. Whether taken with food or on an empty stomach, consistency is paramount for optimal results.

What dosage of Gabapentin is used to treat anxiety?

For anxiety treatment, Gabapentin dosage typically starts at a low dose, around 300 mg per day, and may be gradually increased based on the individual’s response and tolerance. The effective dose for anxiety can vary, with some people requiring up to 1,200 mg per day, divided into multiple doses. 

However, the exact dosage and regimen should always be determined by a healthcare provider that considers your individual needs and medical history.

How long will it take to see an impact when taking Gabapentin?

The timeframe for experiencing the effects of Gabapentin in treating anxiety can vary significantly from person to person. Generally, some people may start to notice an improvement in their anxiety symptoms within the first week of treatment, but for others, it may take several weeks. 

The key factor in determining the onset of effect is how the individual’s body responds to the medication, as well as the specific anxiety condition being treated. For example, a person with generalized anxiety disorder might experience an initial reduction in symptoms like persistent worrying or restlessness within a couple of weeks. However, the full therapeutic effect, including improved sleep and concentration, might take a bit longer.

This variation is a reminder that some may experience relief relatively quickly, and others may require a longer period, sometimes up to several months, for the full therapeutic effects to manifest. It’s important to meet with a healthcare provider who can create a personalized anxiety treatment plan and adjust it over time.

What are the potential side effects of taking Gabapentin? 

Gabapentin, like any medication, can have side effects that vary in intensity and occurrence among individuals. Common side effects include dizziness, fatigue, and drowsiness, which may affect a person’s ability to perform tasks that require alertness. Some people may also experience headaches, blurred vision, or changes in appetite.

It’s also important to be aware of less common but more serious side effects, such as mood changes, memory problems, or difficulty speaking. These symptoms should be reported to a healthcare provider immediately. Long-term use of Gabapentin can lead to physical dependence and withdrawal symptoms if stopped abruptly, so it’s essential to follow a licensed provider’s guidance when discontinuing the medication. 

Gabapentin is classified as a controlled substance in some states due to its potential for abuse and association with harmful side effects when misused. It is classified as a Schedule V controlled substance in Alabama, Kentucky, Michigan, North Dakota, Tennessee, Virginia, and West Virginia. 

This classification aims to regulate its distribution and prevent misuse, recognizing the risks associated with its sedative and psychoactive effects.

Consequently, this status can sometimes complicate the prescribing and refill process, requiring more stringent monitoring and potentially affecting accessibility for patients. Additionally, if dependency is a concern or you have a history of substance abuse, there are non-addictive anxiety medications available.

Licensed providers on Klarity provide personalized treatment. Find a provider that matches your needs and preferences.

Alternative treatments to Gabapentin

While Gabapentin is an effective treatment for some, it’s important to consider alternative options, especially for individuals who may not respond well to it or experience adverse effects. Cognitive Behavioral Therapy (CBT) is a widely recognized anxiety therapy that focuses on changing negative thought patterns and behaviors. 

Additionally, other medications, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are commonly prescribed for anxiety disorders and might be more suitable for certain individuals.

Lifestyle changes can also play a significant role in managing anxiety symptoms. Regular exercise, a balanced diet, and mindfulness practices like meditation can be highly effective in reducing the long-term effects of anxiety. Moreover, some individuals find relief through natural supplements, such as omega-3 fatty acids, though it’s crucial to discuss these with a healthcare provider before starting any new treatment.

Adding Gabapentin to your treatment plan 

Incorporating Gabapentin into your treatment plan for anxiety should be a carefully considered decision that’s made in collaboration with a board-certified healthcare provider. Gabapentin can be an effective addition, particularly for those who haven’t found relief with other treatments. However, it’s essential to consider your overall health, existing medications, and specific anxiety symptoms to ensure that Gabapentin is a suitable choice for your situation.

The process involves a thorough evaluation of your medical history and current health status. Your healthcare provider will assess the potential benefits and risks, taking into account any other medications you’re taking to avoid adverse interactions. It’s crucial to follow the prescribed dosage and administration guidelines, plus keep follow-up appointments to monitor your response to the anxiety treatment.

Do you need a prescription for Gabapentin?

Yes, Gabapentin is a prescription medication, and it’s imperative to obtain it through a licensed healthcare provider. This ensures that you’re receiving the correct dosage and that the medication is appropriate for your specific condition. 

Self-medication or purchasing Gabapentin without a prescription is not advisable due to the potential for misuse, side effects, and interactions with other medications. With the help from providers on Klarity, you can get anxiety and depression medication online, including Gabapentin.

Determine if Gabapentin is right for you with a provider on Klarity

Deciding whether Gabapentin is the right medication for your anxiety is a significant step, and it’s one that shouldn’t be made alone. Consulting with a mental health care provider on Klarity offers you the expertise and guidance needed to make an informed decision. They can evaluate your specific situation, consider your medical history, and prescribe Gabapentin, if applicable.

Find a provider on Klarity today and see if Gabapentin for anxiety is right for your mental health needs.


“Does gabapentin work for anxiety?” Jennifer Larson. SingleCare.

“Gabapentin for Anxiety: Dosing, Side Effects, and More.” Austin Ulrich, PharmD, BCACP. GoodRx.

“Gabapentin for Anxiety: What You Need to Know.” Sophia Monsour, DO. Talkiatry.

“Using Gabapentin for Anxiety and Depression.” Jen Miller, PMHNP-BC. BrightsideHealth.

“Gabapentin For Anxiety: What You Need To Know.” HealthMatch staff. HealthMatch.

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