*Insurance acceptance varies by provider. Klarity is a marketplace platform and does not bill insurance directly.
Protriptyline hydrochloride is an FDA-approved tricyclic antidepressant indicated for the treatment of major depressive disorder in adults.
Interested in getting evaluated for a protriptyline prescription online? Connect with a licensed provider through Klarity Health and receive care in as little as 24 hours.* Providers will assess your symptoms and determine if protriptyline or another treatment is appropriate.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
*Insurance acceptance varies by provider. Klarity is a marketplace platform and does not bill insurance directly.
You’re unique. And your needs are too. You deserve depression treatment from a provider committed to you. That’s why you can find a depression specialist on Klarity Health and access:
From an experienced, board-certified healthcare professional.
or in-person through treatment tailored to you**
Your information is private, secure, and 100% HIPAA compliant.
*Your provider will discuss treatment options with you, which may or may not include medication.
Klarity Health connects you with experienced, licensed providers who specialize in the treatment of depression. Select your state to see available providers.
Getting started involves these steps:
When comparing antidepressants, consider factors such as degree of sedation, side effects, and dosing:
Medication | Uses | Sedating | Dosing |
Protriptyline | Major depression | Low sedation (in TCA group) | Oral tablets 3–4× divided doses |
Nortriptyline | Depression, neuropathic pain (off-label) | Low sedation (in TCA group) | Often once nightly |
Amitriptyline | Depression, insomnia (off-label) | High Sedation | Often once nightly |
Sertraline (Zoloft) | Depression, OCD, PTSD, anxiety | Low sedation (compared to TCAs) | Once daily |
Bupropion (Wellbutrin) | Depression, smoking cessation | No | Once or twice daily (depending on formulation) |
Protriptyline is less sedating among TCAs, \but carries a higher risk of anticholinergic and cardiac side effects overall compared to newer options like SSRIs (sertraline) or SNRIs (bupropion).
Read through stories from real patients who received treatment from healthcare providers on Klarity.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
If you’re having a mental health crisis or experiencing a psychiatric emergency, it’s crucial to seek immediate help from a mental healthcare professional, such as a psychiatrist, psychologist, or therapist. You can also call your local emergency services, visit your nearest emergency room, or contact a crisis hotline, such as the National Suicide Prevention Lifeline, by calling or texting 988 or dialing the Lifeline’s previous phone number, 1-800-273-TALK (1-800-273-8255) in the U.S.