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Accept major insurances and cash-payHSA & FSA accepted; best-value for top quality careSame-day mental health, weight loss, and primary care appointments availableAccept major insurances and cash-payLubiprostone (generic Amitiza) is a prescription medication approved by the FDA to treat chronic idiopathic constipation (CIC) in adults, irritable bowel syndrome with constipation (IBS-C) in women aged 18 and older, and opioid-induced constipation (OIC) in adults with chronic non-cancer pain.
Need a lubiprostone prescription online? Connect with a licensed provider on Klarity Health and, if it’s medically appropriate, get your prescription within 24 hours.*
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
You’re unique. And your needs are too. You deserve IBS-C treatment from a provider committed to you. That’s why you can find an IBS-C specialist on Klarity Health and access:
From an experienced, board-certified healthcare professional.
or in-person through treatment tailored to you**
Your information is private, secure, and 100% HIPAA compliant.
*Your provider will discuss treatment options with you, which may or may not include medication.
Klarity Health connects you with experienced, licensed providers who specialize in the treatment of IBS-C. Select your state to see available providers.
If you’re considering lubiprostone, the process for obtaining a prescription through Klarity Health includes:
Below is a comparison of lubiprostone and other commonly used constipation treatments:
| Medication | Use Case | Side Effect Risk | Cost (Generic) | Administration |
| Lubiprostone | CIC, IBS-C, OIC | Moderate (nausea) | Moderate | Oral capsule |
| Linaclotide (Linzess) | CIC, IBS-C | Moderate (diarrhea) | High | Oral capsule |
| Polyethylene Glycol 3350 | Occasional constipation | Low | Low | Oral powder |
| Prucalopride (Motegrity) | CIC | Moderate (headache) | High | Oral tablet |
| Docusate (Colace) | Stool softener for constipation | Low | Low | Oral capsule |
Lubiprostone is effective for several forms of chronic constipation. It may be preferred in patients who do not respond well to OTC laxatives. Linaclotide is often used for IBS-C, while polyethylene glycol is a cost-effective first-line OTC option. Prucalopride and docusate are alternatives depending on patient needs and tolerance.
Read through stories from real patients who received treatment from healthcare providers on Klarity.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.