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Isotretinoin is an FDA-approved oral retinoic acid derivative used to treat severe nodular acne vulgaris that hasn’t improved with other conventional treatments, such as oral antibiotics.
Interested in getting evaluated for an isotretinoin prescription online? Connect with a licensed provider through Klarity Health and receive care in as little as 24 hours.* Providers will assess your symptoms and determine if isotretinoin or another treatment is appropriate.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
You’re unique. And your needs are too. You deserve acne treatment from a provider committed to you. That’s why you can find an acne specialist on Klarity Health and access:
From an experienced, board-certified healthcare professional.
or in-person through treatment tailored to you**
Your information is private, secure, and 100% HIPAA compliant.
*Your provider will discuss treatment options with you, which may or may not include medication.
Klarity Health connects you with experienced, licensed providers who specialize in the treatment of acne. Select your state to see available providers.
Getting started with isotretinoin prescription online involves these steps:
When choosing an acne treatment, it’s important to compare effectiveness, side effects, and duration:
| Medication | Use Case | Side Effect Risk | Duration | Administration |
| Isotretinoin | Severe nodular or cystic acne resistant to other treatments | (teratogenicity, dry skin, mood effects) | ~15–20 weeks | Oral capsules |
| Oral antibiotics (e.g., doxycycline) | Adjunct therapy in treatment moderate to severe acne | (GD issues, sun sensitivity, avoid in pregnancy) | Weeks–months | Oral tablets, capsule |
| Topical retinoids (tretinoin, adapalene) | Acne | (Irritation, skin dryness) | Varies | Topical |
| Hormonal agents (e.g., oral contraceptives, spironolactone) | Moderate to severe, inflammatory Acne in women | Hormonal effects or hyperkalemia (spironolactone) | Varies | Oral |
Oral isotretinoin is an acne treatment that addresses major acne causes—sebum, inflammation, bacteria, and keratinization—but it carries significantly higher risks than other acne medications. Spironolactone can be used off-label for moderate to severe acne vulgaris in women, although clinical evidence is limited to support its use.
Read through stories from real patients who received treatment from healthcare providers on Klarity.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
PO Box 5098 Redwood City, CA 94063
100 Broadway Street, Redwood City CA, 94063
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PO Box 5098 Redwood City, CA 94063
100 Broadway Street, Redwood City CA, 94063
