fsaHSA & FSA accepted; best-value for top quality care
fsaSame-day mental health, weight loss, and primary care appointments available
Excellent
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based on 0 reviews
fsaNow accepting insurance
fsaHSA & FSA accepted; best-value for top quality care
fsaSame-day mental health, weight loss, and primary care appointments available
Excellent
unstarunstarunstarunstarunstar
staredstaredstaredstaredstared
based on 0 reviews
fsaNow accepting insurance

Same-day syphilis treatment online

Syphilis is a serious but treatable STI. Prompt care from a licensed healthcare provider is important to ensure accurate diagnosis and effective treatment. Providers on Klarity offer online consultations, making it easy to access care from home.

  • Same-day appointments available
  • Affordable and flexible payment options. HSAs & FSAs are accepted
  • No in-person visits required
a picture of a provider who can offer herpes treatment

Online syphilis treatment for you and about you

You’re unique. And your needs are too. You deserve online syphilis treatment from a provider committed to you. That’s why you can find a syphilis specialist on Klarity Health and access:

Syphilis assessment and treatment online in 24 hours*

Syphilis assessment and treatment online in 24 hours*

from a licensed, board-certified healthcare professional.

Syphilis medication prescribed online

Syphilis medication prescribed online

or in-person through treatment tailored to you**

Worry-free booking

Worry-free booking

Free cancellation up to 24 hours before your appointment.

**Your provider will discuss treatment options with you, which may or may not include medication.

Commonly prescribed syphilis medication options

If syphilis is suspected, it’s important to seek timely medical attention. Providers may prescribe antibiotics based on the infection stage and your specific health needs.

Penicillin-based treatments

• Benzathine penicillin G (Bicillin L-A): First-line treatment for all stages of syphilis, including neurosyphilis. Administered via intramuscular injection. FDA-approved.

• Penicillin G procaine: Sometimes used as an alternative. Administered intramuscularly. FDA-approved.

Tetracyclines (for patients allergic to penicillin)

• Doxycycline (Doryx, Vibramycin, Doxy 100): Oral antibiotic used as an alternative in early-stage syphilis. FDA-approved.

• Tetracycline (Achromycin V, Ala-Tet): Another oral option for penicillin-allergic individuals. FDA-approved.

Cephalosporins

• Ceftriaxone (Rocephin): May be used for neurosyphilis or as an alternative. Administered intravenously or intramuscularly. FDA-approved.

Macrolides

• Erythromycin (Ery-Tab, Erythrocin): Occasionally considered in select cases. FDA-approved.

Note: A licensed provider will determine the appropriate treatment based on clinical evaluation.

Book an appointment with experts for syphilis treatment

Klarity Health connects you with experienced, licensed providers who specialize in syphilis treatment. Select your state to see available providers.

Top-rated providers available for you

Amethyst Maxey, FNP-CAPRN
4.98
Amethyst Maxey, FNP-CAPRN
Specializes in Psychiatry, Mental Health
Sawyer Flandreau, FNP-BC
5.0
Sawyer Flandreau, FNP-BC
Specializes in Family Medicine, Mental Health
Melissa Tam, FNP-BC
5.0
Melissa Tam, FNP-BC
Specializes in Internal Medicine, Family Medicine
Derek Timbs, FNP-BC
4.96
Derek Timbs, FNP-BC
Specializes in Weight Loss, Preventive Medicine
Margaret Gallagher, PhD, FNP-BC
5.0
Margaret Gallagher, PhD, FNP-BC
Specializes in Weight Loss, Mental Health
Laurie Jean Foley, PMHNP-BC
5.0
Laurie Jean Foley, PMHNP-BC
Specializes in Weight Loss, Mental Health
Kate Graen, PA-C
4.96
Kate Graen, PA-C
Specializes in Psychiatry, Mental Health
Ernest Emery, AGACNP-BC
5.0
Ernest Emery, AGACNP-BC
Specializes in Psychiatry, Internal Medicine
Noussaiba Ayour, PA
5.0
Noussaiba Ayour, PA
Specializes in Urgent Care, Behavioral Medicine
Amethyst Maxey, FNP-CAPRN
4.98
Amethyst Maxey, FNP-CAPRN
Specializes in Psychiatry, Mental Health
Sawyer Flandreau, FNP-BC
5.0
Sawyer Flandreau, FNP-BC
Specializes in Family Medicine, Mental Health
Melissa Tam, FNP-BC
5.0
Melissa Tam, FNP-BC
Specializes in Internal Medicine, Family Medicine
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Derek Timbs, FNP-BC
4.96
Derek Timbs, FNP-BC
Specializes in Weight Loss, Preventive Medicine
Margaret Gallagher, PhD, FNP-BC
5.0
Margaret Gallagher, PhD, FNP-BC
Specializes in Weight Loss, Mental Health
Laurie Jean Foley, PMHNP-BC
5.0
Laurie Jean Foley, PMHNP-BC
Specializes in Weight Loss, Mental Health
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Kate Graen, PA-C
4.96
Kate Graen, PA-C
Specializes in Psychiatry, Mental Health
Ernest Emery, AGACNP-BC
5.0
Ernest Emery, AGACNP-BC
Specializes in Psychiatry, Internal Medicine
Noussaiba Ayour, PA
5.0
Noussaiba Ayour, PA
Specializes in Urgent Care, Behavioral Medicine
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a picture of syphilis test

What is syphilis

Syphilis is a bacterial STI caused by Treponema pallidum. It spreads through direct contact with syphilitic sores during vaginal, anal, or oral sex. It can also pass from an infected mother to her baby during pregnancy or delivery. If not treated, syphilis can progress through multiple stages and lead to serious health complications.

Causes of syphilis

Syphilis is caused by the bacterium Treponema pallidum. The primary mode of transmission is through sexual contact with an infected person. The bacteria enter the body through mucous membranes or skin abrasions during sexual activity. Non-sexual transmission can occur from mother to child during pregnancy, leading to congenital syphilis. Risk factors include unprotected sex, multiple sexual partners, and having another STI, which can increase susceptibility to syphilis infection.

a picture of how pregnancy may cause syphilis
a picture of common symptoms of syphilis

What are the common symptoms of syphilis?

Syphilis symptoms vary by stage:

  • Primary stage: A painless sore (chancre) at the infection site, appearing 10–90 days post-exposure.
  • Secondary stage: Skin rashes, mucous membrane lesions, fever, swollen lymph nodes, and fatigue.
  • Latent stage: No visible symptoms, but the infection remains in the body.
  • Tertiary stage: Can occur years later, affecting organs like the heart and brain, leading to severe complications.

Note: Early stages are highly contagious. Prompt diagnosis and treatment are crucial.

How to treat syphilis

Treatment depends on the stage of the infection:

Primary, secondary, and early latent stages:

  • Benzathine penicillin G: A single intramuscular injection is typically effective.
  • For penicillin-allergic patients: Oral doxycycline or tetracycline for 14 days.

Late latent and tertiary stages:

  • Benzathine penicillin G: Administered weekly for three weeks.
  • Alternatives: Doxycycline or tetracycline for 28 days if penicillin cannot be used.

Neurosyphilis:

  • Aqueous crystalline penicillin G: Given intravenously every 4 hours for 10–14 days.
  • Alternative: Ceftriaxone administered daily for 10–14 days.

Follow-up testing may be required to ensure treatment effectiveness.

a picture of a provider treating syphilis for the man
a picture of Common medications for syphilis

Common medications to treat syphilis

Prescription medications:

  • Benzathine penicillin G (Bicillin L-A): First-line treatment for all syphilis stages.
  • Penicillin G procaine: Alternative for certain cases.
  • Doxycycline: Oral alternative for penicillin-allergic patients.
  • Tetracycline: Another oral alternative for penicillin-allergic patients.
  • Ceftriaxone: Used for neurosyphilis or as an alternative in specific cases.
  • Erythromycin: Considered in certain situations, though less commonly used.

Note: Over-the-counter medications are not effective against syphilis. Always consult a healthcare provider for appropriate treatment.

When to see a doctor for syphilis treatment

Contact a healthcare provider if you:

  • Notice a painless sore or rash on the genitals, mouth, or hands
  • Have swollen lymph nodes, fatigue, or fever
  • Had unprotected sex with someone who has syphilis
  • Are pregnant and may have been exposed

Early care helps prevent serious complications.

These licensed professionals can recommend the appropriate treatment based on your symptoms.

a picture of seeing an online doctor to treat syphilis

These licensed professionals can recommend the appropriate treatment based on your symptoms.

a picture of a female provider treating syphilis for the woman

What doctors can treat syphilis?

Licensed healthcare providers qualified to diagnose and treat syphilis include:

  • Primary care physicians
  • Infectious disease specialists
  • Dermatologists
  • Obstetricians/gynecologists
  • Nurse practitioners and physician assistants

These professionals can provide appropriate testing, diagnosis, and treatment plans.

How to get a syphilis prescription online

You can connect with a licensed provider on Klarity for an online evaluation. If treatment is medically appropriate, the provider can send a prescription to your pharmacy.

Steps:

  1. Schedule an appointment: Visit Klarity Health to choose a provider.
  2. Attend your consultation: Speak with a provider virtually, often within 24 hours.
  3. Receive your prescription: If necessary, your medication will be sent to a local or online pharmacy.
a picture of getting a syphilis prescription online with a provider

How Klarity Health works

  1. Find a provider and book an appointment in minutes

    1. Meet your provider online for care and a prescription if needed

      1. Pick up your medication at a pharmacy if prescribed

        1. Get 24×7 ongoing support. Book a follow-up anytime

          You’re in good company

          Real testimonials from real patients working with practitioners on the Klarity Health platform.

          FAQs about syphilis treatment online

          *Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.

          The information provided in this article is for educational purposes only and should not be construed as medical advice. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage.  Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.