How to get TRT prescription

Experiencing symptoms of low testosterone and wondering how to get a TRT prescription? You’re not alone. In this guide, you’ll learn exactly what testosterone replacement therapy (TRT) is, why it requires a prescription, and how to get started—whether through a local provider or a telehealth platform.

Curious about starting TRT? Book an appointment with a provider today. 

What is TRT, and how does it work?

Testosterone replacement therapy (TRT) uses medications to help men with clinically confirmed low testosterone—also called hypogonadism—restore their hormone levels. Medications approved by the U.S. Food and Drug Administration to treat hormonal imbalance can include Jatenzo, Kyzatrex, Natesto, Testim, and Testopel and come in many forms, including: 

• Injectables (e.g., testosterone cypionate or enanthate): typically prescribed at 50–200 mg every 2–4 weeks, or 50–100 mg weekly for more consistent hormone levels.
  
• Topical gels and solutions (e.g., 50–100 mg daily gel or 60 mg topical solution).
  
• Other FDA-approved options: XYOSTED (weekly subcutaneous injection), Natesto (nasal gel), Striant (buccal system), transdermal patches, and pellet implants.
  

TRT can relieve symptoms such as fatigue, reduced libido, mood changes, and muscle loss. But before starting TRT, providers require two separate morning blood tests confirming low testosterone levels.

Looking for a prescription for testosterone?

Klarity Health connects you with providers who assess your needs and may prescribe testosterone when clinically appropriate.

Start your consultation

Does TRT have to be prescribed by a doctor?

Yes, therapy has to be prescribed by a doctor because testosterone is a Schedule III controlled substance. To get a TRT prescription, you need a clinical diagnosis of hypogonadism and a prescription from a licensed U.S. provider.

The FDA approves TRT only for men with medical causes of low testosterone. It’s not approved for treating age-related hormone decline alone.

Can you get a TRT prescription online?

 In many states, reputable telehealth services can prescribe TRT if it’s medically appropriate. You’ll complete an online intake, undergo lab testing, and meet with a licensed provider via video consultation.

Once diagnosed, your provider can send your TRT prescription to a local pharmacy or a mail-order service that works with your provider.

How to get a TRT prescription online?

Here’s how the process typically works:

1. Choose a licensed telehealth platform that offers men’s hormone care.
2. Fill out an online questionnaire about your symptoms and health history.
3. Complete two early-morning testosterone blood tests.
4. Schedule a virtual consultation with a licensed provider (physician, nurse practitioner, or physician assistant).
5. If your provider confirms low testosterone, they may prescribe a treatment plan that includes refills and follow-up lab monitoring.

During TRT, your doctor may request monitoring of the following: hematocrit (to track polycythemia risk), liver enzymes, prostate-specific antigen (PSA) levels and digital rectal exam (prostate health), blood pressure, cholesterol levels, and watching for side effects like sleep apnea, clotting, or rare oil microembolism from intramuscular injections.

Need a prescription for testosterone?

Licensed providers on Klarity Health will assess your needs online and prescribe testosterone if it’s clinically appropriate—no waiting room visits.

Start your consultation

Top telehealth platforms to get TRT prescription online

Other ways to get a TRT prescription

If you prefer in-person care, other options include:

• Endocrinologists who are  specialists in hormone conditions
• Urologists who commonly manage male hormone health
• Primary care providers (PCPs) that may prescribe TRT if experienced
• Men’s health clinics that  offer in-office injections and hormone services

What if my provider won’t give me a TRT prescription?

Your provider may deny prescribing TRT if your lab levels don’t meet medical criteria for TRT, you don’t have documented hypogonadism, or if there are medical concerns for which TRT is not a recommended treatment, like prostate cancer or cardiovascular risk. 

If you still want to pursue TRT, you can: 

• Ask for clarification or additional testing
• Request a referral to a urologist or endocrinologist
• Consider a licensed telehealth provider for a second opinion
• Discuss the risks and benefits of treatment thoroughly

How to tell my provider about getting a TRT prescription

If you’re planning to bring up TRT with your provider, be clear and prepared:

• Share your symptoms: “I’ve noticed low energy, low libido, and mood changes.”
• Mention your labs: “My total testosterone was X ng/dL in two separate morning tests.”
• Refer to guidelines: “TRT is commonly used to treat diagnosed hypogonadism when confirmed with labs.”
• Ask about next steps: “Can we go over treatment options and monitoring if I’m a good candidate?”

Getting a TRT prescription online is possible 

TRT is a regulated, medically supervised treatment used to manage hypogonadism, not low testosterone from aging. You’ll need lab tests, a proper diagnosis, and close follow-up to get a prescription and begin treatment. Whether you choose in-person or online care, the right provider will guide you based on your health, goals, and clinical standards.

Ready to get a TRT prescription online?

If you’re exploring testosterone treatment, Klarity Health makes the process simple. Start with labs and connect with a provider who can assess your symptoms and guide your next steps.