Written by Klarity Editorial Team
Published: Nov 27, 2025

Have you ever felt like you’re checking all the right boxes—maintaining friendships, pursuing hobbies, even volunteering—yet still feel an inexplicable emptiness inside? For many young adults, particularly those with histories of childhood trauma or absent parents, this persistent void can be bewildering and frustrating. Despite external achievements and connections, an internal emotional hollowness remains. This phenomenon often signals treatment-resistant depression, a complex condition that requires deeper understanding and specialized approaches.
Treatment-resistant depression affects approximately 30% of those diagnosed with major depressive disorder. For young adults specifically, this resistance can be particularly confusing when they’ve actively implemented commonly recommended lifestyle improvements.
‘I go to therapy, exercise regularly, have good friends, and volunteer at an animal shelter,’ shares Mia, a 23-year-old client at Klarity Health. ‘Everyone tells me I’m doing everything right, but I still wake up feeling empty most days.’
This disconnect between external actions and internal experience is common among young adults with persistent depression, especially when childhood emotional wounds remain unaddressed.
Childhood experiences fundamentally shape our emotional development and neurological patterns. When early trauma or parental emotional absence occurs, the developing brain adapts in ways that can create lasting patterns difficult to break through conventional approaches alone.
Childhood emotional neglect often leads to:
These wounds don’t simply disappear with time or standard self-improvement efforts. As Dr. Joanna Hayes, a psychiatrist with Klarity Health explains, ‘Many young adults with treatment-resistant depression are addressing the symptoms without healing the underlying developmental trauma that created these patterns in the first place.’
Many young adults with persistent depression describe maintaining a ‘public self’ that appears happy and engaged while harboring a private experience of emptiness. This disconnection between external presentation and internal experience can itself become exhausting and further compound feelings of isolation.
‘I became so good at appearing fine that even my closest friends had no idea how much I was struggling,’ explains Jake, 24. ‘Eventually maintaining that facade became another source of depression—I felt like a fraud in my own life.’
Developing authentic self-identity becomes particularly challenging when:
For many young adults, particularly those in conservative environments or transitioning away from religious frameworks, finding meaning and purpose presents additional challenges. Traditional sources of community and existential guidance may feel unavailable or uncomfortable.
Creating meaningful connections requires intentionality, especially when struggling with persistent depression. Effective community-building strategies include:
At Klarity Health, we’ve seen young adults benefit significantly from both traditional therapy and community-based approaches that address this specific challenge of meaning-making and connection.
When standard approaches to depression haven’t provided relief, specialized interventions may be necessary. Effective treatments for persistent depression often include:
Therapies specifically designed to address childhood emotional wounds show particular promise for treatment-resistant depression. These include:
For treatment-resistant depression, medication approaches may need reconsideration:
Many young adults benefit from combining:
Persistent feelings of emptiness despite external connections often reflect early emotional wounds that created patterns of disconnection from self. When childhood emotional needs weren’t adequately met, an internal void can develop that external achievements and relationships alone can’t fill.
Healing from childhood emotional trauma is a non-linear process that varies significantly between individuals. Rather than complete elimination of pain, success often looks like developing greater resilience, self-understanding, and the ability to experience joy alongside continuing to process difficult emotions.
Medication decisions should be made individually with qualified healthcare providers. For some, medication provides essential support while addressing underlying issues; for others, therapy-focused approaches may be more beneficial. At Klarity Health, our providers work with you to determine the most appropriate approach based on your specific needs and history.
For young adults struggling with persistent depression despite doing everything ‘right,’ understanding the connection between childhood emotional wounds and current experiences can be transformative. Recovery involves not just addressing symptoms but healing the core wounds that created them.
The journey toward authentic self-connection and meaningful engagement with life requires patience and specialized support. At Klarity Health, our providers specialize in helping young adults navigate these complex challenges through personalized treatment plans that address both immediate symptoms and underlying causes.
If you’ve been struggling with persistent feelings of emptiness despite your best efforts, know that deeper healing is possible. With the right support and understanding of the unique factors contributing to treatment-resistant depression, finding your way to a more fulfilling experience of life is achievable, even when previous attempts haven’t brought the relief you deserve.
Reach out today to explore how our specialized approach might help you move beyond persistent depression toward authentic connection and meaning.
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