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ADHD

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Adderall vs Quillivant: What’s the difference between tablet and liquid ADHD medication?

Klarity Editorial Team

Written by Klarity Editorial Team

Published: Apr 9, 2024

Medically Reviewed by Dr. Zoe Russell

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Adderall vs Quillivant: What’s the difference between tablet and liquid ADHD medication?
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Choosing between ADHD medications may be overwhelming for some people, especially when comparing similar medications like Adderall vs Quillivant. Each ADHD medication requires time to adapt, with the risk of needing to switch from tablet to liquid form if the first choice doesn’t suit, potentially exacerbating symptoms such as anxiety and insomnia. 

This guide aims to simplify the decision-making process by comparing Quillivant, a liquid stimulant medication, to Adderall, highlighting their differences in form, side effects, contraindications, and costs. With these insights and professional medical advice, determining the most suitable option for your ADHD management can become more straightforward.

Talk to a provider about the right anxiety medication and treatment for you.

If you need a straightforward and reliable healthcare provider who can diagnose and treat your ADHD, get connected with one on Klarity today. Klarity makes it simple to access online ADHD treatment, including prescription medications like Adderall or Quillivant.

To get started, find a provider online or in person with Klarity today. 

QuillivantAdderall
Drug classSchedule II stimulantSchedule II stimulant
Brand / generic statusBrand name for methylphenidate

Brand name for amphetamine salts
Form(s) of the drugLiquid suspensionImmediate release tablets
Standard dosage10mg per liquid dose5mg to 30mg tablets
Conditions treatedFDA-approved uses:
• ADHD
• Narcolepsy
FDA-approved uses:
• ADHD
• Narcolepsy

Off-label uses:
• Depression
• Anxiety
• Bipolar disorder
CostBrand-name Quillivant:
• $400 to $450 for a one-month supply

No generic version for Rx.

Cost may vary depending on insurance coverage.
Brand-name Adderall:
• $8 per 5mg tablet
• $237 for a 30-day supply

Generic form (amphetamine salts):
• $13 for 30 days of 5mg tablets
• $85 for 30 extended-release pills
Side-effectsCommon side effects:
• Decreased appetite
• Weight loss
• Nausea
• Stomach pain
• Dry mouth
• Insomnia
• Increased blood pressure
• Elevated heart rate
• Dizziness
• Irritability
• Anxiety
• Mood swings
• Restlessness

Serious side effects:
• Seizures
• Priapism
• Eyesight changes
• Blurred vision
Common side-effects:
• Decreased appetite
• Weight loss
• Dry mouth
• Nausea
• Headache
• Fever
• Trouble sleeping

Serious side-effects:
• Signs of blood flow problems
• Behavior changes
• Uncontrolled movements
• Shortness of breath
• Irregular heartbeat
• Seizures
• Trouble speaking
Warnings for useContraindications:
• Cardiac abnormalities
• Blood pressure conditions
• History of drug abuse
Drug interactions:
• SSRIs and SNRIs
• Blood pressure medication
• Acid reflux medication
• Blood thinners
• Cold or allergy medication
• Opioid-based medications
• Seizure medication

Quillivant vs Adderall: Key differences 

Quillivant XR, as a liquid medication, introduces a flexible option for ADHD management that sets itself apart from traditional stimulant options like Adderall. This is particularly beneficial if you struggle with swallowing pills or require precise dosage adjustments that are difficult to achieve with tablet forms. The ability to fine-tune doses with Quillivant can lead to more personalized and potentially more effective treatment outcomes for ADHD symptoms.

In comparison, Adderall, available in tablet form, has been a longstanding choice for its effectiveness in improving concentration and reducing impulsivity in ADHD patients. However, the introduction of Quillivant offers its liquid formulation, which may result in a different absorption rate and onset of action, providing an alternative if you’re seeking or needing a change from pill-based medications.

These distinctions underscore the importance of consulting healthcare professionals when considering the best treatment strategy for ADHD, taking into account the unique benefits and considerations of Quillivant as a liquid alternative.

What is Quillivant?

Quillivant XR (methylphenidate hydrochloride) is a liquid stimulant ADHD medication used to treat ADHD in adults and children ages 6 and older. Quillivant XR helps improve focus and decreases impulsivity and hyperactivity by affecting neurotransmitters in the brain that control those behaviors. Quillivant XR contains the same medication as Ritalin.

Forms and dosages

Quillivant XR comes as a liquid suspension. It’s normally taken first thing in the morning, with or without food. Shake the bottle well for 10 seconds and use the included syringe to measure your dose. This medication is time-released and will maintain a steady level of medication in your system for 12 hours following ingestion. 

Starting doses of Quillivant XR begin at 20 milligrams once daily in the morning and can be adjusted in 10-milligram to 20-milligram increments. Daily doses over 60 milligrams have not been studied and aren’t recommended. 

Conditions treated

Quillivant XR is FDA-approved to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy.

Costs

There are currently no generic forms of Quillivant on the market. Prices for individuals without health insurance are typically between $400 and $450 for a one-month supply. Contact your health insurance pharmacy department for more information on your specific pricing under your current plan. 

Side effects

Common side effects of Quillivant XR include but are not limited to:

  • Decreased appetite
  • Weight loss
  • Nausea
  • Stomach pain
  • Dry mouth
  • Insomnia
  • Increased blood pressure
  • Elevated heart rate
  • Dizziness
  • Irritability
  • Anxiety
  • Mood swings
  • Restlessness

Less common but more severe side effects include:

  • Seizures 
  • Priapism 
  • Eyesight changes 
  • Blurred vision

Warnings and drug interactions

Dependency warning: Quillivant XR is a Schedule II stimulant, which means it’s a controlled substance with a high potential for abuse and addiction. Quillivant’s high risk for dependence stems from its ability to stimulate the central nervous system and increase dopamine and norepinephrine levels. This can lead to individuals developing a psychological dependence on this medication. 

Side effects of long-term Quillivant misuse include high blood pressure, agitation, paranoia, and even psychosis. To avoid dependence on Quillivant, follow the prescribed dosage and duration, communicate openly with your healthcare professional about any concerns or side effects, and avoid self-adjusting the medication.

Make sure your ADHD healthcare provider is aware of any cardiac abnormalities you may have. Individuals with cardiac abnormalities or a history of high blood pressure are more susceptible to experiencing heart issues when taking this medication. Stimulants can increase heart rate and blood pressure. Call your doctor immediately if you experience chest pain, shortness of breath, or circulation issues.

Additionally, you should disclose to your healthcare provider any history of mental illness, as Quillivant XR can exacerbate symptoms related to mental illness. 

How to choose between Adderall and Quillivant

Qullivant and Adderall are 2 popular stimulant medications used to treat ADHD symptoms. While they’re largely similar in the way they treat ADHD and in their possible side effects, there are a few differences that might lead you to prefer one over the other. 

Quillivant is available in a liquid suspension form, while Adderall is only available in non-chewable tablets. For this reason, Quillivant may be better for children and people who can’t or struggle to swallow pills. 

Quillivant also has fewer known contraindications than Adderall. If you’re taking allergy, seizure, or opioid-based medications, your provider probably won’t prescribe Adderall for you.

Adderall is the more affordable option of the 2 drugs, which can be the largest factor for those who don’t have adequate health insurance. Quillivant can cost up to $450 for a 30-day supply, and there’s no generic form on the market. Adderall, without insurance, is around $240 for a month’s supply, and the generic version brings that cost to under $100. 

When deciding which of these two medications is right for you, it’s important that you speak with an experienced healthcare provider. You should never try and self-diagnose or self-medicate your symptoms, as there may be more rare side effects or contraindications not mentioned online. 

Get ADHD treatment today with help from Klarity

If you think that Adderall or Quillivant could help you manage your ADHD symptoms, Klarity can help. 

Find a provider for professional ADHD treatment on Klarity today. No insurance is required, and in just 48 hours, you could have a diagnosis and treatment, which may include a prescription for a stimulant medication like Quillivant or Adderall. 

Sources 

Drugs.com. “Comparing Adderall vs Quillivant XR.” https://www.drugs.com/compare/adderall-vs-quillivant-xr

Drugs.com  “Comparing Adderall XR vs Quillivant XR.” “https://www.drugs.com/compare/adderall-xr-vs-quillivant-xr

MedicalNewsToday. “List of ADHD medications: Comparing types.” Jessica Caporuscio, PharmD. Jan. 25, 2024. https://www.medicalnewstoday.com/articles/325201

MedicalNewsToday. “Quillivant XR (methylphenidate).” Alex Brewer, PharmD, MBA. July 25, 2023. https://www.medicalnewstoday.com/articles/drugs-quillivant-xr

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All professional services are provided by independent private practices via the Klarity technology platform. Klarity Health, Inc. does not provide any medical services.
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PO Box 5098 Redwood City, CA 94063

100 Broadway Street, Redwood City CA, 94063

If you’re having an emergency or in emotional distress, here are some resources for immediate help: Emergency: Call 911. National Suicide Prevention Hotline: Call 988. Crisis Text Line: Text Home to 741-741
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