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Guaifenesin is an over-the-counter (OTC) expectorant commonly used to help loosen mucus in the lungs, making coughs more productive. It’s most often used to treat chest congestion associated with common colds, bronchitis, respiratory infections, or allergies. Certain formulations or combination products containing Guaifenesin may require a prescription.
If you have persistent chest congestion, a licensed provider on Klarity can evaluate your symptoms and determine whether guaifenesin online prescription is right for you.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
You’re unique. And your needs are too. You deserve cold & flu treatment from a provider committed to you. That’s why you can find a cold & flu specialist on Klarity Health and access:
From an experienced, board-certified healthcare professional.
or in-person through treatment tailored to you**
Your information is private, secure, and 100% HIPAA compliant.
*Your provider will discuss treatment options with you, which may or may not include medication.
Klarity Health connects you with experienced, licensed providers who specialize in the treatment of cold & flu. Select your state to see available providers.
Most guaifenesin products are available over the counter (OTC), but some extended-release or combination formulations may require a conversation with a healthcare provider. A telehealth appointment is a convenient way to receive professional guidance on whether guaifenesin is appropriate.
Steps to get guaifenesin online:
Providers may suggest further evaluation if your cough is persistent or accompanied by fever, wheezing, or other red-flag symptoms.
Guaifenesin is widely available over the counter, making it one of the most affordable medications for chest congestion. Pricing varies slightly based on brand, dose, quantity, and whether it’s in combination with other medications.
| Pharmacy | 600 mg ER (20 tablets) | 1,200 mg ER (14 tablets) | Syrup (100 mL) |
| GoodRx (Generic) | $6 – $12 | $8 – $16 | $5 – $10 |
| Local Pharmacy | $7 – $14 | $10 – $18 | $6 – $12 |
| Mail-Order Pharmacy | $5 – $11 | $7 – $15 | $4 – $9 |
Ways to save:
• Choose generic guaifenesin (vs. brand-name Mucinex)
• Use bulk-buy discounts for daily use in chronic conditions
• Look for store-brand equivalents at major pharmacies
• Use GoodRx or coupon apps to compare prices across stores
• Extended-release versions are generally more expensive but may reduce the number of daily doses needed.
Guaifenesin is the only FDA-approved oral expectorant for over-the-counter use in the U.S. It’s often combined with other ingredients for comprehensive cold or respiratory relief. However, it differs from other drug classes in its purpose and function.
Comparison to other common respiratory medications:
Why choose guaifenesin?
It’s not ideal for dry coughs or wheezing due to asthma or other chronic lung diseases as those require targeted therapy prescribed by a provider.
Read through stories from real patients who received treatment from healthcare providers on Klarity.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
PO Box 5098 Redwood City, CA 94063
100 Broadway Street, Redwood City CA, 94063
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PO Box 5098 Redwood City, CA 94063
100 Broadway Street, Redwood City CA, 94063
