Admelog (Insulin Lispro): How This Meal-Time Insulin Works and When Telehealth Is Enough

Last updated: August 18, 2026

Admelog is insulin lispro. People also search “admelog insulin,” “admelog solostar,” and “admelog solostar pen.” Those names point to a rapid-acting analog meal-time (bolus) insulin from Sanofi. It is not Humalog even though both are insulin lispro. It is not Lyumjev (insulin lispro-aabc). It is not NovoLog or Fiasp (insulin aspart). It is not Regular human insulin, not NPH, and not analog basal pens such as Lantus or Tresiba. Do not swap Admelog for Humalog on your own even though both are lispro products.

This guide covers how Admelog is usually injected, why it stays clear, how SoloStar pens and vials differ, how pump and mixing rules work, and when a video visit is enough versus when you need labs or the ER. It is educational. It is not a diagnosis or a promise that any specific insulin will be prescribed. Do not change brands, strengths, or units without a clinician.

Want a licensed clinician to review meal-time insulin or an A1C? Klarity Health has 2,000+ licensed providers. Many visits happen online. See online prescription options or browse conditions.

TLDR

• DailyMed lists Admelog (insulin lispro) as a rapid-acting human insulin analog to improve glycemic control in adult and pediatric patients with diabetes mellitus. It is for subcutaneous or intravenous use. Initial U.S. approval: 2017. Presentations are 100 units/mL (U-100) only: 10 mL multiple-dose vial, 3 mL multiple-dose vial, and 3 mL single-patient-use SoloStar pen (DailyMed Admelog).
• Inject Admelog under the skin of the abdomen, thigh, upper arm, or buttocks within 15 minutes before a meal or immediately after a meal. It should generally pair with an intermediate or long-acting insulin when you inject it. The SoloStar pen dials in 1-unit steps from 1 to 80 units. Each pen holds 300 units.
• Do not mix Admelog with any other insulin for injection. Do not mix or dilute Admelog in a pump. Change Admelog in the pump reservoir at least every 7 days or per the pump manual, whichever is shorter, or after the reservoir exceeds 98.6°F (37°C).
• IV Admelog is under medical supervision only. Staff dilute it to 0.1 to 1 unit/mL in 0.9% sodium chloride. Infusion bags are stable 24 hours refrigerated or up to 4 hours at room temperature. A clinician may also dilute Admelog 1:1 with sterile 0.9% sodium chloride for subcutaneous use (U-50 equivalent); do not do that at home unless a clinician taught you that step.
• Do not use Admelog during hypoglycemia or if you are allergic to insulin lispro or an excipient. Never share a SoloStar pen, needle, or syringe.
• In-use vials last 28 days refrigerated or at room temperature. An in-use SoloStar pen lasts 28 days at room temperature only; do not put the opened pen back in the fridge. Unused refrigerated stock can last until the labeled expiration date. Do not freeze it.
• Cleveland Clinic lists insulin lispro (Humalog) onset about 10 to 15 minutes, peak 1 to 3 hours, duration 3 to 5 hours. Admelog is the same molecule class; follow the Admelog label for timing, not a neighbor’s Humalog habit (Cleveland Clinic injectable insulin chart).
• Typical home glucose targets many adults use: 80 to 130 mg/dL before meals and under 180 mg/dL two hours after a meal starts. A reading under 70 mg/dL is low. If you are sick and a reading is 240 mg/dL or higher, check ketones (CDC manage blood sugar).
• Medicare covers many telehealth visits from home anywhere in the U.S. through December 31, 2027 (HHS telehealth policy). Seizure, loss of consciousness, chest pain, or blood sugar that will not come up is 911, not a video visit.

What Admelog is trying to fix

Type 1 diabetes means the pancreas makes little or no insulin. Type 2 diabetes means the body resists insulin and often does not make enough of it. Glucose stays in the blood. Over years that raises the chance of heart disease, stroke, kidney disease, nerve damage, and eye disease. NIDDK notes some people with type 2 diabetes can control glucose with food, activity, sleep, and weight change. Many still need pills or insulin. Over time you may need more than one medicine (NIDDK insulin and medicines).

Meal-time insulin replaces the burst a working pancreas would release when you eat. Admelog is labeled as a rapid-acting analog. DailyMed says to inject it within 15 minutes before a meal or immediately after a meal. That window is earlier than the “start of the meal or within 20 minutes after you start eating” language on Lyumjev and Fiasp. Follow your own prescription, not a neighbor’s timing.

MedlinePlus groups insulin lispro solution under Admelog and Humalog. The products are not automatically interchangeable at the pharmacy counter. Always check the carton and pen name before every dose (MedlinePlus insulin lispro).

Typical home targets the CDC lists for many adults:

• Before a meal: 80 to 130 mg/dL
• Two hours after the start of a meal: under 180 mg/dL

Blood sugar under 70 mg/dL is low. If you are sick and a reading is 240 mg/dL or higher, check ketones. High ketones can signal diabetic ketoacidosis, which is an emergency. A pump failure or a missed bolus can raise ketones quickly. DailyMed warns that pump malfunction can lead to hyperglycemia and ketoacidosis. You need backup pens or vials and a plan for injections if the pump fails.

Related Klarity guides: Humalog and NovoLog, Lyumjev (insulin lispro-aabc), Fiasp (insulin aspart), and Apidra (insulin glulisine).

How Admelog is supplied

DailyMed lists only U-100 (100 units/mL), clear and colorless:

• 10 mL multiple-dose vial
• 3 mL multiple-dose vial
• 3 mL single-patient-use SoloStar prefilled pen (carton of 5)

Inspect the liquid before every dose. It should look clear and colorless. Do not use it if you see particles or color. Always read the carton and pen label. Accidental mix-ups between insulin products can cause severe hypoglycemia.

The SoloStar pen is for one patient only. It dials 1-unit steps up to 80 units per injection. Each pen holds 300 units. If you cannot select your full prescribed dose, finish with a new pen. Take a new pen out of the refrigerator at least 1 hour before you inject; cold insulin hurts more. Do a 2-unit safety test before each shot. After you press the button and see “0,” count slowly to 10 before you pull the needle out.

Use a U-100 syringe with the vial. Do not reuse needles. A blocked needle can deliver the wrong dose.

Meal timing, sites, and mixing

Give subcutaneous Admelog within 15 minutes before a meal or immediately after a meal. Sites listed on the label: abdomen, thigh, upper arm, or buttocks. Rotate within the same region. Do not inject into lipodystrophy or localized cutaneous amyloidosis. Do not inject into tender, bruised, scaly, hard, scarred, or damaged skin.

When you inject (rather than pump) Admelog, it should generally pair with an intermediate or long-acting insulin. That is the basal-bolus pattern many people already use with Lantus, Tresiba, Toujeo, Levemir, or NPH.

DailyMed is explicit for injection: do not mix Admelog with any other insulin. That is stricter than some Humalog U-100 language that allows mixing with NPH if you draw Humalog first and inject immediately. If you used to mix Humalog and NPH in one syringe, do not assume the same rule applies after a switch to Admelog.

A clinician may dilute Admelog 1:1 with sterile 0.9% sodium chloride for subcutaneous use, which yields a concentration equal to U-50. Unused diluted product lasts up to 24 hours refrigerated or 4 hours at room temperature. That is a taught clinic step, not a kitchen experiment.

Pumps and IV

Admelog can go in a compatible external insulin pump as a continuous subcutaneous infusion. Confirm your pump’s user manual lists Admelog. Change insulin in the reservoir at least every 7 days, or sooner if the pump manual says so, or after the reservoir exceeds 98.6°F (37°C). Change infusion sets and insertion sites per the pump maker. Do not dilute or mix Admelog in the pump.

If the pump fails, high sugar and ketones can rise fast. DailyMed tells patients to keep backup injection insulin and know how to use it. A video visit can help you plan that backup. It cannot restart a failed pump in the moment.

IV Admelog is under medical supervision only, with glucose and potassium monitoring. Staff dilute it to 0.1 to 1 unit/mL in 0.9% sodium chloride. Prepared bags last 24 hours refrigerated or up to 4 hours at room temperature. This is hospital or clinic work, not a home task.

Who should not use it and what to watch

Do not use Admelog during an episode of hypoglycemia. Do not use it if you have hypersensitivity to insulin lispro or an excipient. Never share a SoloStar pen, needle, or syringe, even if you change the needle.

Change insulin strength, manufacturer, type, injection site, or method only under close medical supervision, with more frequent glucose checks. Hypoglycemia can be life-threatening. Risk rises when dose, other glucose-lowering drugs, meals, or activity change, and in people with kidney or liver impairment or hypoglycemia unawareness.

Hypokalemia can also be life-threatening. Clinicians monitor potassium in people at risk. Severe allergy, including anaphylaxis, can occur. Stop Admelog and get emergency care for whole-body rash, swelling of the face or throat, or trouble breathing.

Thiazolidinediones (pioglitazone, rosiglitazone) plus insulin can cause fluid retention and heart failure. Watch for sudden weight gain, swelling, or shortness of breath. A clinician may cut or stop the TZD.

Common reactions listed on DailyMed include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus, and rash.

DailyMed also reports Admelog plus insulin glargine U-100 in 26-week adult trials: type 1 (NCT02273180) mean A1C change about −0.40% versus −0.46% on another lispro; type 2 (NCT02294474) about −0.86% versus −0.80%. Those studies support non-inferiority to another insulin lispro product. They are not a reason to switch brands without a clinician.

When a telehealth visit is enough

A licensed clinician can often review home glucose logs, CGM exports, A1C results, meal timing, missed doses, and whether Admelog versus Humalog or another analog still matches your day. Many people need help after a pharmacy substitution, a new basal, or a jump in overnight lows. Medicare currently covers many non-behavioral telehealth visits from home with no geographic restriction through December 31, 2027.

Insurance may or may not prefer Admelog over Humalog, Lyumjev, or another lispro. Coverage varies by plan, formulary tier, and prior authorization. Verify benefits before you assume a specific pen is on your plan. Klarity does not promise that any insulin will be prescribed or covered.

Go to the ER or call 911 for seizure, loss of consciousness, chest pain, severe allergic reaction, or blood sugar that will not rise with your usual treatment. Persistent vomiting with high ketones is also emergency care, not a same-day video slot.

Ready to talk through meal-time insulin? See online prescription options or browse conditions.

FAQ

Is Admelog the same as Humalog?

No. Both are insulin lispro meal insulins, but they are different products with different manufacturers, mixing rules, and devices. MedlinePlus groups them on one page. DailyMed still treats Admelog as its own label. Do not interchange them without a clinician.

Can I put Admelog in a pump?

Yes, if your pump manual lists Admelog. Do not mix or dilute it in the pump. Change the reservoir at least every 7 days or sooner if the pump maker says so. Keep backup pens or vials.

Can I mix Admelog with NPH?

DailyMed says do not mix Admelog with any other insulin for injection. That differs from some Humalog U-100 mixing language. Follow the Admelog label.

When do I inject it?

The label says within 15 minutes before eating or right after a meal, under the skin. Your clinician may tighten that window based on your CGM pattern.

What if the pharmacy filled Humalog instead?

Call the prescriber before you switch. Timing, mixing, and pen handling are not identical. Check the pen or vial name before every dose.

Disclaimer

This article is for education. It is not medical advice, a diagnosis, or a guarantee of insurance coverage. Coverage and prior authorization vary by plan. Confirm benefits with your insurer. A licensed clinician decides whether any medicine is appropriate. Klarity Health has 2,000+ licensed providers. Emergency symptoms need 911 or an emergency department.