Written by Klarity Editorial Team
Published: Jul 10, 2026

Humana plans in Mississippi may cover depression treatment under your mental health benefits, which are protected by federal Medicare parity requirements for Medicare Advantage plans. Coverage may include psychiatric evaluations, medication management, and follow-up appointments, depending on your specific plan, deductible status, and in-network provider selection. Klarity Health offers online depression treatment and works with many insurance plans. You can check whether your Humana plan may cover care at Klarity before booking.
Following its exit from the commercial health insurance market in 2024, Humana currently serves Mississippi residents primarily through Medicare Advantage (MA) plans. Plan types available in Mississippi may include Gold Plus HMO, HumanaChoice PPO, R/H PPO, and Honor HMO-POS options. Mental health parity protections for Humana Medicare Advantage plans in Mississippi are governed by CMS under 42 CFR Part 422, rather than state commercial insurance parity statutes such as Miss. Code Ann. § 83-9-353 et seq. Medicare Advantage plans that include mental health benefits must generally comply with federal parity requirements as administered by CMS.
Medicare Advantage mental health benefits: Humana Medicare Advantage plans in Mississippi may cover depression evaluation and medication management under their mental health benefits. Coverage details, including prior authorization requirements, in-network providers, and cost-sharing, vary by specific plan and county. Review your Evidence of Coverage (EOC) document for your plan’s depression treatment benefit details.
Medications through Humana Pharmacy Solutions: Humana Medicare Advantage plans include Part D pharmacy benefits managed by Humana Pharmacy Solutions (HPS). Depression medications commonly covered through HPS may include: SSRIs such as sertraline (Tier 1–2), fluoxetine (Tier 1), escitalopram (Tier 1–2), and paroxetine (Tier 1); SNRIs such as venlafaxine (Tier 1–2) and duloxetine (Tier 2); and other antidepressants including bupropion (Tier 1), mirtazapine (Tier 1–2), and trazodone (Tier 1). All standard antidepressants are non-scheduled medications — EPCS requirements do not apply to antidepressant prescriptions.
Prior authorization: Generic antidepressants typically do not require prior authorization. Branded or newer antidepressants may require prior authorization through HPS. Your Klarity provider can assist with prior authorization documentation when needed.
Medicaid note: Humana also administers Medicaid managed care plans in some states. If you are enrolled in a Humana Medicaid plan in Mississippi, benefit terms differ from Medicare Advantage — contact Humana Medicaid member services for your specific plan’s depression treatment coverage.
Cost-sharing: Medicare Advantage cost-sharing for mental health visits and Part D medications varies by plan. Review your Humana Evidence of Coverage or call Humana member services to confirm your specific cost-sharing for depression treatment and antidepressant prescriptions.
Humana Medicare Advantage plans in Mississippi may cover depression treatment, including psychiatric evaluations and medication management, under mental health benefits governed by CMS 42 CFR Part 422. Coverage specifics depend on your specific plan, in-network providers, and prior authorization requirements. Verify your benefits by reviewing your Evidence of Coverage or calling Humana member services.
Humana Medicare Advantage Part D benefits through Humana Pharmacy Solutions may cover a range of antidepressant medications in Mississippi. Generic SSRIs and SNRIs are typically on lower cost-sharing tiers. Branded antidepressants may require prior authorization. Check the Humana drug formulary tool or call the pharmacy number on your Humana card to confirm your medication’s coverage and cost-sharing.
Klarity Health works with many insurance plans and network status may vary by state and plan type. Use Klarity’s benefits check tool or contact Humana member services to confirm whether Klarity providers are in-network with your specific Humana Medicare Advantage plan in Mississippi before booking.
Copays for depression treatment with Humana in Mississippi depend on your specific Medicare Advantage plan type, cost-sharing structure, and whether your provider is in-network. Review your Evidence of Coverage or call Humana member services at 1-800-448-6262 for your specific cost-sharing details.
Referral requirements depend on your Humana plan type in Mississippi. Gold Plus HMO and Honor HMO-POS plans typically require a primary care physician referral for specialist mental health services. HumanaChoice PPO and R/H PPO plans generally allow direct access to in-network mental health providers. Confirm your plan’s referral requirements with Humana before scheduling depression treatment.
Many Humana Medicare Advantage plans may cover telehealth-based depression treatment in Mississippi, including virtual psychiatric evaluations and medication management sessions. Telehealth benefit terms vary by plan. Confirm your plan’s online mental health coverage with Humana before scheduling your first virtual appointment.
To verify depression treatment coverage with Humana in Mississippi: (1) log into MyHumana or the Humana app and view your mental health benefits; (2) call member services at 1-800-448-6262; (3) review your Evidence of Coverage document; (4) use Klarity Health’s benefits verification tool; or (5) call the pharmacy number on your Humana card to confirm antidepressant coverage under Part D. Confirm prior authorization requirements before scheduling care.
Humana Medicare Advantage plans in Mississippi — including Gold Plus HMO, HumanaChoice PPO, R/H PPO, and Honor HMO-POS — include Part D pharmacy benefits through Humana Pharmacy Solutions that may cover antidepressants. Coverage details, tier placement, and prior authorization requirements vary by plan. Contact Humana Pharmacy Solutions or Humana member services to confirm your plan’s depression medication coverage.
Insurance coverage varies by plan, insurer, and state. The information on this page is intended as general guidance only and does not constitute a guarantee of benefits. Telehealth provider availability may vary by state. Please verify your specific plan’s mental health coverage with your insurer or through Klarity’s benefits check before booking.
If you are enrolled in a Humana Medicaid managed care plan, please contact Humana Medicaid member services directly, as Medicaid benefit terms differ from Medicare Advantage plans described on this page.
Check if your Humana plan may cover depression treatment in Mississippi
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