Wegovy (semaglutide) and phentermine are effective weight loss medications with distinct mechanisms, costs, and safety profiles. Wegovy offers long-term, robust weight loss via appetite suppression, while phentermine is a short-term stimulant-based appetite suppressant. Wegovy is an injectable approved for chronic use, leading to about 15% weight loss over 68 weeks, whereas phentermine, a generic oral drug, provides 3-5% loss over 12 weeks. Cost-wise, phentermine is significantly cheaper (~$1.50 per pill), while Wegovy costs around $1,430/month. Insurance coverage varies; phentermine often has easier access and is less costly, but Wegovy may be covered with prior authorization. Both medications have side effects: Wegovy's include gastrointestinal issues and rare serious risks like pancreatitis, while phentermine's side effects involve cardiovascular concerns. Your choice depends on health history, weight loss goals, and cost considerations—consult a healthcare provider to determine the best option for you.
Many individuals seeking weight loss want to understand the differences between Wegovy and phentermine. Both medications are FDA-approved but serve different roles, mechanisms, and durations of use.
Contains semaglutide, a GLP-1 receptor agonist. It mimics natural hormones that increase satiety, reduce hunger, and regulate blood sugar, leading to sustained appetite suppression and weight loss.
Acts as a stimulant, releasing neurotransmitters like norepinephrine, dopamine, and epinephrine. This reduces appetite quickly and provides an energy boost, aiding short-term weight loss.
Wegovy is approved for adults and children 12+ with obesity or overweight with health conditions, for weight management and cardiovascular risk reduction. Phentermine is approved for adults 16+ for short-term weight loss, typically up to 12 weeks.
Common side effects include nausea, vomiting, diarrhea, and rare risks like pancreatitis, gallbladder disease, and thyroid tumors. Not suitable for those with a personal or family history of thyroid cancer.
May cause increased blood pressure, insomnia, mood changes, and rare severe effects such as pulmonary hypertension and heart valve issues. It is a controlled substance with potential for misuse.
Phentermine is more affordable, often covered easily by insurance. Wegovy costs significantly more but may be covered depending on insurance plans, often requiring prior authorization or step therapy. Cost savings programs and coupons may reduce expenses.
Your decision should consider your health history, safety profile, weight loss goals, and cost. Wegovy is preferred for long-term, significant weight loss, especially in those with comorbidities. Phentermine may suit short-term needs or cost constraints.
Discuss your health status, preferences, and goals with a qualified provider. On Klarity, you can book same-day virtual appointments with licensed professionals who can prescribe medications if appropriate.
Interested in safe, effective weight loss treatment? Visit Klarity Health to find a provider, review your options, and begin your journey with expert support. Appointments are generally available within 24 hours, with no need for in-person visits in many cases.
Important: The information provided is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider before starting, stopping, or changing any medication or treatment plan.
Wegovy can produce noticeable weight loss within a few months, with significant results seen after 68 weeks. Phentermine may show effects within weeks but is intended for short-term use.
Combining these medications is not typically recommended due to potential safety concerns. Always consult your healthcare provider for personalized advice.
Wegovy is FDA-approved for long-term use and has a safety profile suited for extended weight management, whereas phentermine is generally limited to short-term use.
Wegovy costs about $1,430/month, while phentermine, a generic, costs roughly $1.50 per pill. Over long periods, phentermine is significantly more affordable.
Wegovy commonly causes gastrointestinal issues; phentermine may cause increased heart rate, blood pressure, and nervousness. Serious side effects require medical attention.
Ready to start your weight loss journey? Visit Klarity Health to find a provider and book a same-day appointment. Get expert guidance and prescriptions if suitable, all from the comfort of your home.