How Does GLP-1 Work for Weight Loss & Who Should Try It?

Medically Reviewed by Dr. Kasra Tayebi

GLP-1 reduces hunger, promotes fullness, and helps regulate blood sugar, making it effective for weight loss in overweight adults after medical evaluation.

What is a GLP-1 agonist?

GLP-1 (glucagon-like peptide 1) is a hormone produced in the pancreas that helps control blood sugar and stimulate insulin release. GLP-1 agonists are medications designed to mimic this hormone, binding to its receptors to reduce hunger and improve glucose regulation.

How does GLP-1 work for weight loss?

GLP-1 agonists imitate natural GLP-1, making you feel full faster and reducing appetite. This leads to decreased calorie intake, weight loss, and better blood sugar control. Many patients report fewer cravings and less frequent thoughts of food.

GLP-1 drugs for weight loss

FDA-approved GLP-1 medications include drugs like semaglutide (Ozempic, Wegovy), dulaglutide, and tirzepatide (Mounjaro). They are administered via weekly injections or oral tablets, used alongside diet and exercise to promote weight loss.

Who should try GLP-1 agonists for weight loss?

Adults with BMI ≥27, especially those with weight-related health conditions like high blood pressure or diabetes, are candidates. Candidates should consult a healthcare provider to assess medical history, BMI, and suitability.

Contraindications to using GLP-1 agonists for weight loss

Patients with hypersensitivity, pancreatitis history, medullary thyroid cancer risk, severe kidney disease, gastroparesis, or certain endocrine syndromes should avoid GLP-1 medications. Always discuss medical history with your provider.

Benefits and side effects of GLP-1

Benefits include weight loss, reduced blood pressure, improved lipid profile, and lower risk of fatty liver, heart, and kidney disease. Side effects may include nausea, vomiting, diarrhea, and rare gastrointestinal issues, which often lessen over time.

What to expect if trying GLP-1 for weight loss

Initial weight loss averages around 5-10% over several months. Responses vary based on medication dose, individual tolerance, and adherence. Side effects are manageable with medical supervision. Lifestyle changes enhance results.

How to get GLP-1

Obtain a prescription through a licensed healthcare provider, such as via Klarity. They will evaluate your health, BMI, and medical history to determine eligibility. Medications should be purchased from licensed pharmacies, not online sources.

Are there natural alternatives for GLP-1?

Some foods and herbs, like tea, curcumin, cinnamon, berberine, and resveratrol, may promote natural GLP-1 secretion. However, their effects are less potent than medications and should be discussed with your healthcare provider before use.

How to get help for weight loss support today

If you're feeling stressed about weight or health, consulting a licensed provider on Klarity can help you start medication-supported weight management. Appointments are available within 24 hours for personalized care and prescriptions if appropriate.

FAQs about how GLP-1 works

How do GLP-1s make you lose weight?

They mimic natural hormones, reducing hunger and increasing fullness, which lowers calorie intake and promotes weight loss.

How does someone qualify to use GLP-1 for weight loss?

Adults with BMI ≥27, especially with weight-related health issues, after a medical evaluation and consultation with a licensed provider.

Does GLP-1 speed up metabolism?

GLP-1 primarily reduces appetite and slows digestion; it does not directly increase basal metabolic rate.

How quickly do you lose weight with GLP-1?

Average weight loss is about 5-10% over 3 to 6 months, varying based on dosage, lifestyle, and individual response.

How can I get a GLP-1 prescription?

Consult a licensed healthcare provider via Klarity. They will evaluate your health, BMI, and medical history to prescribe if appropriate.

Start your weight loss journey today

Book an appointment with a licensed provider on Klarity for personalized, same-day consultations and prescriptions if suitable. Achieve your health goals with professional guidance and support.

Klarity offers: Same-day online healthcare, weight management, mental health, and primary care services. Accepts major insurances, HSA/FSA, and cash-pay options.

Contact & Bookings

Visit helloklarity.com to sign up or log in, schedule your appointment, and start your personalized weight loss plan today.