Metformin, primarily used for type 2 diabetes, is also prescribed off-label for weight loss. It improves insulin sensitivity, reduces hunger, and promotes fat burning, helping individuals lose at least 5% of body weight over a year. Get evaluated online on Klarity for a personalized plan.
Metformin is a medication originally designed to treat type 2 diabetes. It’s also used off-label to assist with weight loss by influencing insulin sensitivity and appetite regulation. Although not FDA-approved specifically for weight loss, it can be prescribed by healthcare providers to support weight management goals.
Metformin enhances insulin sensitivity, decreases the amount of sugar your liver produces, and may alter hormones that control hunger. It can also affect gut microbiome composition, leading to reduced appetite and increased fat burning. These mechanisms contribute to weight reduction over time.
Metformin is FDA-approved for individuals over age 10 with type 2 diabetes. Off-label use for weight loss is prescribed by healthcare providers based on individual health profiles. Candidates typically include those with insulin resistance or metabolic syndrome, but only a doctor can determine suitability.
To obtain a prescription, you can consult a licensed healthcare provider via Klarity Health. During your evaluation, the provider will assess your symptoms and health history. If appropriate, they will prescribe metformin and send it to your preferred pharmacy—online or local.
Metformin is available as immediate-release or extended-release tablets, or as a liquid. Typical starting doses range from 500 mg twice daily to 850 mg once daily, taken with meals. Your provider may increase the dose gradually up to a maximum of 2550 mg daily.
For children, starting doses are lower, with gradual increases based on age and tolerance. Always follow your healthcare provider’s instructions for dosing and adjustments.
Common side effects include diarrhea, nausea, vomiting, gas, and stomach discomfort. Serious but rare risks involve lactic acidosis, vitamin B12 deficiency, allergic reactions, and kidney problems. Report any adverse effects to your provider and FDA MedWatch.
Discuss potential side effects before starting, and report any unusual symptoms promptly.
Generic metformin tablets are affordable: about $28 for 30 immediate-release tablets and $18 for extended-release. Brand-name versions like Glucophage and Glumetza are significantly more expensive, often exceeding $1,500 without discounts.
While metformin typically results in about 5% weight loss, others like Ozempic or Mounjaro can produce up to 10-14%, and Zepbound up to 20%. Despite being less potent, metformin remains a good option for those who cannot take other medications.
Medications like Ozempic and Mounjaro are FDA-approved for weight management and blood sugar control, with side effects including nausea, vomiting, and headaches.
Yes, if your healthcare provider deems it appropriate for weight management, they can prescribe metformin off-label.
In the U.S., metformin requires a prescription. Online evaluations via Klarity Health facilitate safe, legal access.
Weight loss varies; on average, people may lose around 5% body weight over a year. Results depend on diet, exercise, and individual response.
Metformin generally produces less weight loss than Mounjaro or Ozempic but remains effective, especially for those who prefer or need oral medication options.
Ozempic typically results in greater weight loss but involves injections. Metformin may be suitable for those seeking an oral option or with specific health considerations.
Our licensed providers create personalized weight loss plans, including medication prescriptions when appropriate, dietary guidance, and ongoing support. Book an appointment online in minutes and start your health journey today.
Important: This content is for educational purposes only. Always consult a qualified healthcare provider before starting or adjusting medication. Providers on Klarity Health are independent practitioners with clinical autonomy; prescriptions are based on individual assessments.
Visit helloklarity.com to sign up, book your evaluation, and connect with licensed providers who specialize in weight management and medication therapy. Your health and safety are our priority.