Pamelor (nortriptyline) is mainly approved for depression; Tofranil (imipramine) is approved for depression and childhood bedwetting. Both are TCAs with similar side effects but different off-label uses and costs.
Both Pamelor (nortriptyline) and Tofranil (imipramine) are tricyclic antidepressants (TCAs) approved by the FDA to treat major depressive disorder. They belong to the same medication class but differ in approved uses, side effects, and off-label applications.
Both medications are used off-label for various conditions such as neuropathic pain, anxiety disorders, irritable bowel syndrome, and headache prevention, depending on individual patient needs.
Both drugs may cause dry mouth, dizziness, nausea, sedation, and other side effects. Serious risks include serotonin syndrome, cardiac issues, and overdose potential. Close medical supervision is essential.
TCAs are generally avoided during pregnancy due to potential risks but are considered safe during breastfeeding in trace amounts. Always consult your healthcare provider for personalized advice.
Generic forms of both medications are affordable with coupons. Brand-name prices are significantly higher. Both require a prescription from a licensed healthcare provider.
Yes. Both Pamelor and Tofranil are prescription medications. They should only be taken under medical supervision due to potential adverse effects and drug interactions.
TCAs carry a black box warning for increased risk of suicidal thoughts, especially in young adults under 24. Overdose can be fatal, so careful monitoring and adherence to prescribed doses are critical.
If you are considering depression treatment, Klarity offers online evaluations and prescriptions from licensed providers. Book an appointment today to start your personalized mental health care from home—get seen within 48 hours.
Pamelor is mainly approved for depression and off-label uses like headache prevention, while Tofranil is approved for depression and childhood bedwetting, with different off-label applications.
TCAs are generally avoided during pregnancy due to risks like preterm delivery but are considered safe during breastfeeding in trace amounts. Consult your doctor for personalized guidance.
Generic Pamelor can cost under $15/month with coupons; Tofranil can be about $10/month with discounts. Brand prices are much higher without insurance.
Yes. Both medications require a licensed healthcare provider's evaluation and prescription due to potential side effects and interactions.
To access personalized depression treatment quickly, book an appointment on Klarity. Our licensed providers can diagnose and prescribe online, with appointments available within 24-48 hours.