Pitolisant (brand name Wakix) is an FDA-approved medication used to treat excessive daytime sleepiness (EDS) and cataplexy in adults with narcolepsy, and EDS in children aged 6 and older. Access your prescription easily through Klarity’s online platform.
", "Pitolisant is a first-in-class histamine H₃ receptor antagonist/inverse agonist that promotes wakefulness by increasing histamine levels in the brain. It is available as film-coated tablets in 4.45 mg and 17.8 mg strengths, typically taken once daily in the morning.
", "By blocking histamine H₃ receptors, pitolisant enhances histamine release, helping reduce daytime sleepiness and the frequency of cataplexy episodes, without the stimulant effects or high abuse potential of traditional medications.
", "Approved for adults and children aged 6 and older diagnosed with narcolepsy. Patients should consult a healthcare professional to determine if pitolisant is appropriate for their condition.
", "Typically administered once daily in the morning. Dosage adjustments are made gradually. Full benefits may take several weeks, up to 8, to manifest. Always follow your provider’s instructions.
", "Appointments are generally available within 24 hours. In some cases, in-person evaluations may be required depending on federal and state regulations for controlled substances.
", "Pitolisant offers a non-controlled, once-daily dosing alternative with a lower abuse risk compared to stimulant medications like Adderall or modafinil. It is suitable for patients seeking wakefulness promotion without stimulant side effects.
", "| Medication | ", "Type | ", "Abuse Potential | ", "Schedule | ", "Notes | ", "
|---|---|---|---|---|
| Pitolisant (Wakix) | ", "Histamine H₃ antagonist | ", "Low | ", "Non-controlled | ", "Once daily, lower abuse risk | ", "
| Modafinil | ", "Stimulant | ", "Moderate | ", "Schedule IV | ", "Potential for misuse, requires monitoring | ", "
| Adderall | ", "Stimulant | ", "High | ", "Schedule II | ", "High abuse potential, controlled substance | ", "
Licensed healthcare providers on Klarity, including neurologists, sleep medicine specialists, and trained nurse practitioners, can evaluate and prescribe pitolisant. Providers assess your symptoms during a confidential telehealth consultation.
", "Visit Klarity’s provider directory to see available specialists in your state.
", "Klarity accepts major insurance plans and offers affordable cash-pay options. The cost for a virtual consultation varies; many appointments are available within the same day. Check your insurance coverage for prescriptions and follow-up visits.
", "HSA and FSA accounts are accepted for eligible treatments.
", "Important: This content is for educational purposes only. Prescription medications, especially controlled substances like pitolisant, require a proper medical evaluation and prescription from a licensed provider. Follow your healthcare professional’s advice.
", "Schedule a virtual consultation on Klarity. A licensed provider evaluates your symptoms and, if appropriate, prescribes pitolisant to your preferred pharmacy.
", "No, pitolisant is a non-controlled wake-promoting agent with a lower abuse risk, unlike traditional stimulants such as Adderall or methylphenidate.
", "Fast access to treatment, convenience of virtual visits, personalized care from licensed providers, and prescriptions within 24 hours on Klarity.
", "Yes, Klarity accepts major insurances and offers cash-pay options. Coverage varies; check with your insurer for details.
", "Depending on federal and state regulations, some prescriptions may require in-person assessments, especially for controlled medications like pitolisant.
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