Concerta vs Vyvanse for ADHD: what’s the difference?

When choosing a medication to help manage your attention deficity hyperactivity disorder (ADHD) symptoms, it can be difficult to know which is best for your needs and goals. Though most ADHD medications are stimulant-based and have similar effects on the central nervous system, each formula is just a little different than the other. Concerta vs Vyvanse are two such medications.

In this article, we compare them, so you can choose the best one based on factors like drug interactions, possible side effects, and cost. 

If you suspect you have ADHD, stimulant medications like Concerta or Vyvanse could be effective in managing your condition. Always speak to a medical professional about your symptoms, rather than attempting to self-diagnose yourself online. To receive a professional diagnosis and affordable, convenient treatment for ADHD, connect with a provider for Klarity matches patients with licensed healthcare providers in their state for comprehensive online ADHD treatment on Klarity today.

What is Concerta?

Concerta (Methylphenidate) is a central nervous system stimulant that works by affecting neurotransmitters in the brain that control hyperactivity, focus, and impulsivity. This medication is a schedule II controlled substance primarily prescribed to help fight the symptoms of ADHD. Methylphenidate is similar to the active ingredients in ADHD medications Daytrana and Ritalin.

Forms and dosages for Concerta

Concerta is a once-a-day extended-release tablet that lasts up to 10 hours. Dosages come in 18, 27, 36, 54, and 72 milligrams. Typically, adults start off with an 18 milligrams dose and increase the potency until the desired result is achieved. Concerta shouldn’t be crushed or chewed.

Concerta has a unique delivery method called OROS, which stands for osmotically controlled release oral-delivery system. When Concerta is first taken, the outside shell dissolves and 22% of the total dose is delivered. Three inner compartments release at different times throughout the day as the intestines absorb the chambers, releasing the medication and resulting in a time-release effect that lasts up to 10 hours. 

One-sixth of the medication is never released and absorbed, so each capsule of Concerta actually delivers a few milligrams less than what’s described. The medical community has yet to agree on the supremacy of backloaded, increasing doses versus steady release delivery systems. 

Concerta comes in “generic” formulations designated methylphenidate ER from six different pharmaceutical manufacturers, and all come in the aforementioned strengths. This can cause quite a bit of confusion as all of these medications seem similar, but five of these products are actually inferior to the “branded generic” product. Recently, the FDA downgraded the quality ratings of two of these products. 

Consumers should stay away from the inferior generic Concerta products. Ask your pharmacist which one it dispenses. The “branded generic” form of Concerta is shaped like a barrel, has a tiny hole on one end where the medication bleeds out, and should still bear the manufacturer name: ALZA. 

Conditions treated by Concerta

Concerta is FDA-approved for use in individuals with attention-deficit hyperactivity disorder (ADHD) and sleeping disorders like narcolepsy.

The cost of Concerta

Without insurance, a one-month supply of brand-name 36 milligram Concerta tablets is approximately between $250 and $300. A generic supply of Concerta for the same exact quantity is approximately $1,446 a month according to drugs.com. That price can vary depending on the pharmacy you choose. The generic extended-release form ranges from $193 to $559 according to drugs.com,

Online coupons are available that can knock down the price some. For more accurate pricing under your current health insurance plan, contact your provider’s customer service department. 

Concerta side effects

Most patients taking Concerta don;t experience many side effects if any. Common side effects of Concerta include but aren’t limited to:

• Decreased appetite
• Dry mouth
• Sleep disruption
• Dizziness
• Stomach ache
• Increased sweating
• Headache
• Nausea
• Weight loss
• Irritability

Severe but rare side effects of Concerta include:

• Priapism
• Eyesight changes
• Blurred vision

Warnings and drug interactions for Concerta

Concerta may exacerbate certain conditions or dangerously interact with medications you’re currently taking. Before taking Concerta, have a candid discussion with your doctor concerning any of the following issues if you’ve experienced them in the past or are currently experiencing them:

• Heart or blood-pressure-related issues
• Mental illness or mental health issues
• Circulation issues
• Substance abuse

Read your prescription’s accompanying literature and be open and honest about your medical history when speaking with your healthcare provider. This is especially important if you have a history of substance abuse. 

Dependency warning: Concerta, classified as a Schedule II stimulant, poses a significant risk of dependency when misused. Concerta misuse can have adverse effects on individuals’ physical and psychological well-being, such as mood swings, irritability, and anxiety. Prolonged or excessive use may lead to withdrawal symptoms upon discontinuation, including fatigue, depression, and intense cravings.

To mitigate the risk of dependency, it is crucial to strictly adhere to the prescribed dosage and duration as directed by a healthcare professional. Altering the dosage without medical supervision can increase the likelihood of dependency. Regular communication with your healthcare provider is essential to evaluate medication effectiveness, address concerns, and monitor any potential side effects.

What is Vyvanse?

Vyvanse (lisdexamfetamine dimesylate) is a once-a-day time-released stimulant medication used to primarily treat attention-deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. Available since FDA approval in 2007, Vyvanse is a Schedule II federally controlled substance, although it is not considered a narcotic. 

Vyvanse works by targeting neurotransmitters in the brain that regulate behaviors like impulsivity, hyperactivity, and focus. 

Forms and dosages of Vyvanse

Vyvanse is what’s known as a prodrug, i.e., an inert medication that does not reach activation until it is processed by the liver. Because of this, and because it takes longer to process, Vyvanse has a lower risk of abuse and addiction as compared to medications like Adderall and Ritalin. 

This ADHD medication comes in 5, 20, 30, 40, 50, 60, and 70 milligram doses. Vyvanse comes in chewable tablets, too, and follows the same guidelines for dosages and strength. Vyvanse is taken first thing in the morning with or without food. Capsules should be swallowed whole and not crushed or chewed. 

Conditions treated with Vyvanse

Vyvanse is FDA-approved to treat ADHD, some sleeping disorders like narcolepsy, and binge eating disorder (BED). 

What Vyvanse costs

Vyvanse is currently only in brand name form and does not have a generic version. The branded form of Vyvanse is one of the costlier ADHD medications on the market. A one-month supply of brand-name Vyvanse without health insurance is approximately between $1,371 according to drugs.com.

For more information on pricing under your current health insurance plan, contact your provider’s pharmacy department. 

Side effects when taking Vyvanse

Most people taking Vyvanse do not experience side effects. Common side effects of Vyvanse include but are not limited to:

• Anxiety
• Diarrhea
• Dizziness
• Dry mouth
• Irritability
• Nausea
• Trouble sleeping
• Vomiting
• Weight loss
• Upper stomach pain
• Decreased appetite
• Loss of appetite

Less common side effects of Vyvanse include:

• Blurred vision
• Irregular or fast heartbeat
• Mood changes, including aggression and depression
• Muscle twitching
• Uncontrolled movements
• Blood flow problems in the fingers and toes
• Swelling in the ankles and feet
• Rapid and unexplained weight loss

Warnings and drug interactions for Vyvanse

Vyvanse is a stimulant and can therefore cause health issues for those suffering from cardiac abnormalities, circulation issues, mental health issues, and substance abuse. Speak candidly with your healthcare provider about your medical history before taking this medication, and be sure to read your prescription’s accompanying literature for accurate information on warnings and drug interactions. 

Dependency warning: Vyvanse, a Schedule II stimulant and a controlled substance, has the potential for addiction and dependency when misused, posing risks to a person’s physical and psychological well-being. Individuals with a history of substance abuse or addiction are especially vulnerable. Discuss addiction concerns with your healthcare provider before starting Vyvanse.

To minimize dependency risks, strictly adhere to the prescribed dosage and frequency as directed by your healthcare provider. Maintain open communication with your healthcare provider to evaluate effectiveness, address concerns, and ensure proper management of Vyvanse. Store the medication securely to prevent misuse, and seek medical guidance as needed to promote safe and responsible use.

Concerta vs Vyvanse: bow to choose between them

There are a number of similarities between Concerta vs Vyvanse. They are both stimulant medications used to reduce ADHD symptoms, and are both long-acting, meaning their effects can last about 12 hours.

The main difference between these prescription drugs is how they are absorbed by the body. Vyvanse is a prodrug, meaning that it won’t begin working until it has been metabolized by the body. For this reason, it takes between 1 and 2 hours for patients to notice the difference in their behavior as a result of Vyvanse.

Concerta contains methylphenidate, the same drug as Ritalin. However, Concerta works faster than Ritalin, thanks to an osmotic-controlled release delivery system. When you take a Concerta tablet, this method works to release the drug into your system slowly throughout the day, rather than all at once.

Due to its delivery system, Concerta only comes in tablet form and cannot be split or crushed. Vyvanse is available in capsules and chewable tablets, making it a better choice for those who have difficulty swallowing pills.

Children and adults with heart conditions cannot take either of these medications, as stimulants can worsen these conditions. Additionally, those with Tourette’s syndrome and glaucoma should avoid Concerta, but they should be able to safely take Vyvanse.

Vyvanse vs Concerta: which one is right for you?

Vyvanse and Concerta are both time-released central nervous system stimulants, but they have two different delivery systems. For this reason, it can be difficult to know which one will be more effective for your ADHD without the help of a licensed healthcare provider. You should always speak to a medical professional who can diagnose your ADHD and prescribe the medication that best suits you.

Let a provider on Klarity Health help you find the tight ADHD medication

If you have ADHD and are looking for an affordable and convenient way to choose a medication, like Concerta vs Vyvanse, a provider on Klarity can help. Connect you with a licensed healthcare provider in your state who can evaluate, diagnose, and treat your symptoms.

Find a provider today and finally start experiencing relief from your ADHD symptoms.